Google Scholar Link

  1. Parra, M., Coppola, M., Hellmann, H. (2024) PDX proteins from Arabidopsis thaliana as novel substrates of Cathepsin B: Implications for vitamin B6 biosynthesis regulation. FEBS J. accepted

  2. Landers, J., Mooney, S., Smalley, S., Al-Saharin, R., Knoblauch, M., Hellmann, H. (2023) Generation of stable transgenic Brassica napus cv. Jet Neuf cell cultures as a tool to investigate in planta protein function. Plant Cell Tiss Organ Cult https://doi.org/10.1007/s11240-023-02538-y
  3. Corbridge, E., MacGregor, A., Al-Saharin, R., Garneau, M.G., Smalley, S., Mooney, S., Roje, S., Bates, P.D., Hellmann, H. (2023) Brassica napus plants gain improved salt-stress tolerance and increased storage oil biosynthesis by interfering with CRL3BPM activities. Plants 12(5), 1085.
  4. Al-Saharin, R., Mooney, S., Dissmeyer, N., Hellmann, H. (2022) Using CRL3BPM E3 ligase substrate recognition sites as tools to impact plant development and stress tolerance in Arabidopsis thaliana. Plant Direct 6:e474
  5. Navarre, D.A., Zhu, M., Hellmann, H. (2022) Plant antioxidants affect human and gut health, and their biosynthesis Is influenced by environment and reactive oxygen species. Oxygen, 10.3390/oxygen2030025
  6. Smalley, S., Hellmann, H. (2022) Exploring possible approaches using ubiquitylation and sumoylation pathways in modifying plant stress tolerance. Plant Sci. 319, 111275
  7. Al-Saharin, R.; Hellmann, H.; Mooney, S. (2022) Plant E3 Ligases and Their Role in Abiotic Stress Response. Cells 11, 890.
  8. Gingerich, D.J., Christians, M.J., Hellmann, H., Stone, S.L. (2021) Editorial: Structure, Function, and Evolution of E3 Ligases and Targets. Front Plant Sci10.3389/fpls.2021.767281
  9. Novikova, I.V., Zhou, M., Du, C., Parra, M., Kim, D.N., VanAernum, Z.L., Shaw, J.B., Hellmann, H., Wysocki, V.H., Evans, J.E. (2021) Tunable hetero-assembly of a plant pseudoenzyme-enzyme complex. ACS Chem Biol 16, 2315-2325.
  10. Beathard, C., Mooney, S., Al-Saharin, R., Goyer, A., Hellmann, H.A. (2021) Characterization of Arabidopsis thaliana R2R3 S23 MYB transcription factors as novel targets of the ubiquitin proteasome-pathway and regulators of salt stress and abscisic acid response. Front Plant Sci. fpls.2021.629208
  11. Hellmann, H., Goyer, A., Navarre, D.A. (2021) Antioxidants in Potatoes: A Functional View on One of the Major Food Crops Worldwide. Molecules 26, 2446
  12. Al-Saharin, R., Mooney, S., Hellmann, H. (2020) Plant E3 Ligases as Versatile Tools for Novel Drug Development and Plant Bioengineering. Book Chapter in Protein Degradation with New Chemical Modalities: Successful Strategies in  Drug Discovery and Chemical Biology Drug Discovery; Series No. 74. Ed. by H. Weinmann and C. Crews. Royal Society of Chemistry, pp. 184-211
  13. Liu, Y., Peters, W.S., Froelich, D.R., Howell, A.H., Mooney, S., Evans, J.E., Hellmann, H.A., Knoblauch, M. (2020) Aspartate Residues in a Forisome-forming SEO Protein are Critical for Protein Body Assembly and Ca2+-Responsiveness. Plant Cell Physiol, pcaa093.
  14. Lellis, A.D., Patrick, R.M., Mayberry, L.K., Lorence, A., Campbell, Z.C., Roose, J.L., Frankel, L.K.,Bricker, T.M., Hellmann, H.A., Mayberry, R.W., Zavala, A.S., Choy, G.S., Wylie, D.C., Abdul-Moheeth, M., Masood, A., Prater, A.G., van Hoorn, H.E., Cole, N., Browning, K.S. (2019) eIFiso4G augments synthesis of specific plant proteins involved in normal chloroplast function. Plant Physiol. pii: pp.00557.2019. doi: 10.1104/pp.19.00557
  15. Goyer, A., Picard, M., Hellmann, H.A., Mooney, S.L. (2019) Effect of low temperature storage on the content of folate, vitamin B6, ascorbic acid, chlorogenic acid, tyrosine, and phenylalanine in potatoes. J. Sci. Food Agric. doi: 10.1002/jsfa.9750
  16. Mooney, S., Al-Saharin, R., Choi, C.M., Tucker, K., Beathard, C., Hellmann, H.A. (2019) Characterization of Brassica rapa RAP2.4-Related Proteins in Stress Response and as CUL3-Dependent E3 Ligase Substrates. Cells 8:336
  17. Novikova, I.V., Sharma, N., Moser, T., Sontag, R., Liu, Y., Collazo, M., Cascio, D., Shokuhfar, T., Hellmann, H., Knoblauch, M., Evans, J.E. (2018) Protein Structural Biology Using a Cell-Free Platform from Wheat Germ. Adv. Struct. Chem. Imag. 4:13
  18. Navarre, D.A., Moehninsi, M., Lin, S., Hellmann, H. (2018) Nutritional properties and enhancement/ biofortification of potatoes. Book Chapter Wang-Pruski, G. (ed.), Achieving sustainable cultivation of potatoes Volume 1: Breeding improved varieties, Burleigh Dodds Science Publishing, Cambridge, UK, (ISBN: 978 1 78676 100 2)
  19. Parra, M., Stahl, S., Hellmann, H. (2018) Vitamin B6 and Its Role in Cell Metabolism and Physiology Cells, 7, 84
  20. Lu, M., Hellmann, H.A., Liu, Y., Wang, W. (2018) Editorial: Protein Quality Controlling Systems in Plant Responses to Environmental Stresses. Front. Plant Sci. 9:908.
  21. Mullendore, D.L., Ross-Elliott, T., Liu, Y., Hellmann, H.A., Roalson, E.H., Peters, W.S., Knoblauch, M. (2018) Non-dispersive phloem-protein bodies (NPBs) of Populus trichocarpa consist of a SEOR protein and do not respond to cell wounding and Ca2+. Peer J. 6:e4665
  22. Ghosh, D., Lin, Q., Xu, J., Hellmann, H.A. (2017) Editorial: How Plants Deal with Stress: Exploration through Proteome Investigation. Front Plant Sci. 8:1176.
  23. von Arnim A.G., Hellmann H.A. (2016) Meeting report: processing, translation, decay - three ways to keep RNA sizzling. Plant Cell Environ. 39, 2624-2628.
  24. Navarre, D.A., Shakya, R., Hellmann H. (2016) Vitamins, Phytonutrients, and Minerals in Potato. In: Singh, J., Kaur, L. (Eds.), Advances in Potato Chemistry and Technology 2nd ed. Academic Press, pp. 117–166.
  25. Chen L., Bernhardt A., Lee J.H., Hellmann H. (2015) Identification of Arabidopsis MYB56 as a novel substrate for CRL3BPM E3 ligases. Mol. Plant 8, 242-250.
  26. Choi C., Gray W.M., Mooney S., Hellmann H. (2014) Composition, Roles, and Regulation of Cullin-based Ubiquitin E3 ligases. The Arabidopsis Book 12, e0175
  27. Leuendorf, E., Mooney, S., Chen, L., Hellmann, H. (2014) Arabidopsis thaliana PDX1.2 is critical for embryo development and heat shock tolerance. Planta 240, 137-146
  28. Navarre, D.A., Goyer, A., Payyavula, R., Hellmann, H. (2014). Nutritional Characteristics of Potatoes. In Roy Navarre (Eds.), The Potato Botany production and uses (pp 310-344). CABI
  29. Smeekens, S. and Hellmann H.A. (2014) Sugar Sensing and Signaling in Plants. Front. Plant. Physiol. 5, 113
  30. Mooney, S., Chen, L., Kühn, C., Navarre, D.A., Knowles, N.R., Hellmann, H. (2013) Genotype Specific Changes in Vitamin B6 Content and the PDX Family in Potato. BioMed Res Int Article ID 389723.
  31. Chen, L., Lee, J.H., Weber, H., Tohge, T., Witt, S., Roje, S., Fernie, A.R., Hellmann, H. (2013) Arabidopsis BPM proteins function as substrate adapters to a CUL3-based E3 ligase to affect fatty acid metabolism in plants. Plant Cell 25, 2253-2264.
  32. Chen, L., and Hellmann, H. (2013) Plant E3 Ligases: Flexible Enzymes In A Sessile World. Mol Plant 10.1093/mp/sst005
  33. Funck D., Clauss K., Frommer W.B., Hellmann H. (2012) The Arabidopsis CstF64-like RSR1/ESP1 protein participates in glucose signaling and flowering time control. Front. Plant. Physiol. 3, 80.
  34. Fitzpatrick T.B., Basset G.J.C., Borel P., Carrari F., DellaPenna D., Fraser P.H., Hellmann H., Osorio S., Rothan C., Valpuesta V., Caris-Veyrat C., Fernie A.R. (2012) Vitamin deficiencies in humans: Can Plant Science help? Plant Cell, 24, 395-414.

  35. Biedermann S., Mooney S., Hellmann H. (2011) Recognition and Repair Pathways of Damaged DNA in Higher Plants, Selected Topics in DNA Repair, Clark C. Chen (Ed.), InTech Publishing ISBN: 978-953-307-606-5.

  36. Leasure C.D., Tong H.-Y., Hou X.-W., Shelton  A., Minton M., Esquerra R., Roje S., Hellmann H., He Z.-H. (2011) root uv-b sensitive Mutants Are Suppressed by Specific Mutations in ASPARTATE AMINOTRANSFERASE2 and by Exogenous Vitamin B6. Mol. Plant 4, 759-770.
  37. Biedermann S. and Hellmann H. (2011) WD40 and CUL4-based E3 Ligases: Lubricating all Aspects of Life. Trends Plant Sci. 16, 38-46.
  38. Leuendorf J.E., Osorio S., Szewczyk A., Fernie A.R., Hellmann H. (2010) Complex assembly and metabolic profiling of Arabidopsis thaliana plants overexpressing vitamin B6 biosynthesis proteins. Mol. Plant 3, 890-903.
  39. Bernhardt A, Mooney S, Hellmann H. (2010) Arabidopsis DDB1a and DDB1b are critical for embryo development. Planta 232, 555-566.
  40. Biedermann S. and Hellmann H. (2010) The DDB1a interacting proteins ATCSA-1 and DDB2 are critical factors for UV-B tolerance and genomic integrity in Arabidopsis thaliana. Plant J. 62, 404-415.
  41. Mooney S., and Hellmann H. (2010) Vitamin B6: Killing two birds with one stone? Phytochemistry 71, 495-501.
  42. Hellmann H., and Sutton Mooney (2010) Vitamin B6: A Molecule for Human Health? Molecules 15, 442-459.
  43. Hellmann H. (2010) Book review: Vitamins and Hormones: Folic Acid and Folates. Am. J. Human Biol. 22, 139
  44. Weber H., and Hellmann H. (2009) Arabidopsis thaliana BTB/POZ-MATH proteins interact with members of the ERF/AP2 transcription factor family. FEBS J. 22, 6624 - 6635.
  45. Mooney S., Leuendorf J.E., Hendrickson C., Hellmann H. (2009) Vitamin B6: a long known compound of surprising complexity. Molecules 14, 329-351.
  46. Lytovchenko A., Beleggia R., Schauer N., Isaacson T., Leuendorf J.E., Hellmann H., Rose J.K., Fernie A.R. (2009) Application of GC-MS for the detection of lipophilic compounds in diverse plant tissues. Plant Methods 5:4.
  47. Leuendorf J.E., Genau A., Szewczyk A, Mooney S., Drewke C., Leistner E., Hellmann H. (2008) The PDX1 family is structurally and functionally conserved between Arabidopsis thaliana and Ginkgo biloba. FEBS J. 275, 960–969.
  48. Weber, H., Hano, P., Hellmann, H. (2007) The Charming Complexity of Cul3. Internat. J. Dev. Plant. 1, 178-184.
  49. Bernhardt A., Lechner E., Hano P., Schade V., Dieterle M., Anders M., Dubin M.J., Benvenuto G., Bowler C., Genschik P., Hellmann H.  (2006) CUL4 associates with DDB1a and DET1 and its down regulation affects diverse aspects of development in Arabidopsis thaliana. Plant J. 47, 591-603.
  50. Wagner S., Bernhardt A., Leuendorf J.E., Drewke C., Lytovchenko A., Mujahed N., Gurgui C., Frommer W.B., Leistner E., Fernie A.R., Hellmann H. (2006) Analysis of the Arabidopsis rsr4-1/pdx1-3 Mutant Reveals the Critical Function of the PDX1 Protein Family in Metabolism, Development, and Vitamin B6 Biosynthesis. Plant Cell 18, 1722-1735.
  51. Weber, H., Bernhardt, A., Dieterle, M., Hano, P., Mutlu, A., Estelle, M., Genschik, P., Hellmann, H. (2005) Arabidopsis AtCUL3a and AtCUL3b form complexes with members of the BTB/POZ-MATH protein family. Plant Physiol. 137, 83-93.
  52. Ren, C., Pan, J., Peng, W., Genschik, P., Hobbie, L., Hellmann, H., Estelle, M., Gao, B., Peng, J., Sun, C., Xie, D. (2005) Point mutations in Arabidopsis Cullin1 reveal its essential role in jasmonate response Plant J. 42, 514–524.
  53. Figueroa, P., Gusmaroli, G., Serino, G., Habashi, J., Ma, L., Shen, Y., Feng, S., Bostick, M., Callis, J., Hellmann, H., Deng, X.W. (2005) Arabidopsis Has Two Redundant Cullin3 Proteins That Are Essential for Embryo Development and That Interact with RBX1 and BTB Proteins to Form Multisubunit E3 Ubiquitin Ligase Complexes in Vivo. Plant Cell 17, 1180-1195.
  54. Gingerich, D.J., Gagne, J.M., Salter, D.W., Hellmann, H., Estelle, M., Vierstra, R.D. (2005) Cullin 3A and B assemble with members of the broad complex/tramtrack/bric-A-brac (BTB). J. Biol. Chem. 280, 18810-18821.
  55. Hellmann, H., Hobbie, L., Chapman, A., Dharmasiri, S., Dharmasiri, N., del Pozo, C., Reinhardt, D., Estelle, M. (2003) Arabidopsis AXR6 encodes CUL1 implicating SCF E3 ligases in auxin regulation of embryogenesis. EMBO J. 22, 3314-3325.
  56. Risseeuw E.P., Daskalchuk T.E., Banks T.W., Liu E., Cotelesage J., Hellmann H., Estelle M., Somers D.E., Crosby W.L. (2003) Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis. Plant J. 34, 753-767.
  57. Dharmasiri S., Dharmasiri N., Hellmann H., Estelle M. (2003) The RUB/Nedd8 conjugation pathway is required for early development in Arabidopsis. EMBO J. 22, 1762-1770.
  58. Gray W.M., Hellmann H., Dharmasiri S., Estelle M. (2002) Role of the Arabidopsis RING-H2 Protein RBX1 In RUB Modification and SCF Function. Plant Cell 14, 2137-2144.
  59. Hellmann, H. and Estelle M. (2002) Plant Development: Regulation by Protein Degradation. Science 297, 793-797.
  60. Shen W.H., Parmentier Y., Hellmann H., Lechner E., Dong A., Masson J., Granier F., Lepiniec L., Estelle M., Genschik P. (2002) Null Mutation of AtCUL1 Causes Arrest in Early Embryogenesis in Arabidopsis. Mol. Biol. Cell. 13, 1916-1928.
  61. del Pozo J.C., Dharmasiri S., Hellmann H., Walker L., Gray W.M., Estelle M. (2002) AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis Cullin AtCUL1 is required for auxin response. Plant Cell 14, 421-433.
  62. Deuschle K., Funck D., Hellmann H., Daschner K., Binder S., Frommer W.B. (2001) A nuclear gene encoding mitochondrial Delta-pyrroline-5-carboxylate dehydrogenase and its potential role in protection from proline toxicity. Plant J. 27, 345-356.
  63. Hellmann, H., Barker, L., Funck, D., Frommer, W.B. (2000) The Regulation of Assimilate Allocation and Transport. Aust. J. Plant. Physiol. 27, 583-594.
  64. Barker, L., Kühn, C., Weise, A., Schulz, A., Gebhardt, C., Hirner, B., Hellmann, H., Schulze, W., Ward, J.M., Frommer, W.B. (2000). SUT2, a Putative Sucrose Sensor in Sieve Elements. Plant Cell 12, 1153-1164.
  65. Hellmann, H., Funck, D., Rentsch, D., Frommer, W.B. (2000) Hypersensitivity of an Arabidopsis thaliana Sugar Signalling Mutant Towards Exogenous Proline Application. Plant Physiol. 123, 779-789.
  66. Lalonde, S., Boles, E., Hellmann, H., Ward, J.M., Frommer, W.B. (1999) A Dual Function of Plant Sugar Carriers in Transport and in Sugar Sensing? Plant Cell 11, 707-726.
  67. Martin, T., Hellmann, H., Schmidt, R., Willmitzer, L., Frommer, W.B. (1997) Identification of Mutants in Metabolically Regulated Gene Expression. Plant J. 11, 53-62.

 

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